WHY CHOOSE ASIMOV

Cell line development services

Our experienced team uses the CHO Edge System and state-of-the-art equipment to perform CLD & upstream process development.

How it works

We use our proprietary software, Kernel, for codon optimization, vector design and biophysical simulation to make a panel of expression vectors.

You request a cell line development campaign for a specific biologic and provide us with an amino acid sequence.

GS-KO CHO host transfected

Vectors are used to make a panel of stable pools which are assessed for quality and titer performance.

Stable pool generated

The lead pool is cloned out with monoclonality verification via pre and post deposition imaging using the Cytena F-sightTM and Solentim Cell Metric®.

Clones characterized and banked

24-48 clones are progressed for fed batch analysis at Ambr® 15 scale

Bioreactor Ambr® 15 run

Additional process development using Ambr® 250 and bench top bioreactors is also available.

Stability studies and additional analytical characterization can be performed at your request.

CONTACT INFO

hello@asimov.com

+1 (617) 539-8659